The paper “MRI/Photoluminescence Dual-Modal Imaging Magnetic PLGA Nanocapsules for Theranostics” has been recently published in the January issue of the journal MDPI Pharmaceutics.
Congratulations to N&N PhD student Yajie Zhang and to Anna Roig!
This study has been carried out in collaboration with Anna Rosell group from Vall d´Hebron Research Institute in Barcelona.
Congratulations to the authors: Jana S. Segmehl, Anna Laromaine, Tobias Keplinger, Anna May-Masnou, Ingo Burgertab and Anna Roig for their new publication entitled: Magnetic wood by in situ synthesis of iron oxide nanoparticles via a microwave-assisted route. The paper was first published on 9th of March 2018 in the Journal of Materials Chemistry.
Abstract:
Functional materials with high porosity and hierarchical structures are highly demanded for numerous material applications. In this study a magnetic hybrid material derived from wood and superparamagnetic iron oxide nanoparticles (SPIONs), was synthesized by microwave-assisted thermal decomposition. This novel in situfunctionalization approach resulted in a homogeneous distribution of the integrated inorganic component within the entire complex wood cell wall structure, which was previously not achieved. In a detailed investigation based on confocal Raman microscopy imaging, transmission electron microscopy, and optical microscopy the precipitated phase and the resulting hybrid structure were characterized. Magnetic measurements revealed the impact of the anisotropic wood scaffold on the integrated magnetic functionality and confirmed the isotropic superparamagnetic characteristics of the in situ precipitated nanoparticles. Therewith, it is clearly demonstrated, that the anisotropic properties of the obtained hybrid material result from the particle organization in the given spruce wood structure and no alteration of particle properties is induced by the presence of the lignocellulosic material.
We congratulate the autos Laura Gonzalez-Moragas, Si-Ming Yu, Núria Benseny-Cases, Stephen Stürzenbaum, Anna Roig and Anna Laromaine for their recently accepted paper: Toxicogenomics of iron oxide nanoparticles in the nematode C. elegans. This research arises from a collaboration of the N&N group, the ALBA Synchrotron Light Source (MIRAS line) and the King’s College London.
Here you can read the abstract of the paper:
We present a mechanistic study of the effect of iron oxide nanoparticles (SPIONs) in C. elegans combining a genome-wide analysis with the investigation of specific molecular markers frequently linked to nanotoxicity. The effects of two different coatings were explored: citrate, an anionic stabilizer, and bovine serum albumin, as a pre-formed protein corona. The transcriptomic study identified differentially expressed genes following an exposure to SPIONs. The expression of genes involved in oxidative stress, metal detoxification response, endocytosis, intestinal integrity and iron homeostasis was quantitatively evaluated. The role of oxidative stress was confirmed by gene expression analysis and by synchrotron Fourier Transform infrared microscopy based on the higher tissue oxidation of NP-treated animals. The observed transcriptional modulation of key signaling pathways such as MAPK and Wnt suggests that SPIONs might be endocytosed by clathrin-mediated processes, a putative mechanism of nanotoxicity which deserves further mechanistic investigations.
Citation:
Toxicogenomics of iron oxide nanoparticles in the nematode C. elegans
Laura Gonzalez-Moragas, Si-Ming Yu, Núria Benseny-Cases, Stephen Stürzenbaum, Anna Roig and Anna Laromaine
Nanotoxicology, Accepted manuscript online: 15 Jun 2017. DOI: 10.1080/17435390.2017.1342011
A recent manuscript entitled “A recoverable ruthenium aqua complex supported onto silica particles: an efficient epoxidation catalyst“, by M. Isabel Romero, Ingrid Ferrer, Xavier Fontrodona, Anna Roig and Montserrat Rodríguez, has been accepted in CHEMISTRY – A European Journal (Accepted manuscript online: 11 January 2017; D
This article is the product of a collaboration with the Group of Catalysis and Sustainability of the University of Girona.
The article reports the synthesis and catalytic performance of hybrid materials formed by a molecular ruthenium aqua complex anchored onto silica mesoporous and silica coated magnetic particles. The catalytic results and the reutilization of these hybrid materials highlight their performance in the epoxidation of alkenes.
Abstract
The preparation and characterization of new complexes with a phosphonated trpy ligand (trpy-P-Et) and a bidentate pyridylpyrazole (pypz-Me) ligand, with formula [RuII(trpy-P-Et)(pypz-Me)X]n+ (X = Cl, n= 1, 2; X=H2O, n=2, 3) is described, together with the anchoring of 3 onto two types of supports: mesoporous silica particles (SP) and silica coated magnetic particles (MSP). The aqua complex 3 is easily obtained through reflux of 2 in water and displays a bielectronic Ru(IV/II) redox process. It has been anchored onto SP and MSP supports through two different synthetic strategies, yielding the heterogeneous systems SP@3 and MSP@3 that have been fully characterized by IR, UV-vis, SEM, CV and DPV. Catalytic olefin epoxidation has been tested with the molecular complex 3 and the SP@3 and MSP@3 heterogeneous counterparts, including the reuse of the heterogeneous systems. The MSP@3 material can be easily recovered by a magnet facilitating their reusability.
Download article.
The paper “Electrochemically active thin carbon films with enhanced adhesion to silicon substrates” (Pengfei Niu, Laura Asturias-Arribas, Martí Gich, César Fernández-Sánchez, and Anna Roig) has been published online as a Just Accepted Manuscript in ACS Applied Materials & Interfaces (DOI: 10.1021/acsami.6b07347).
In this study, authors demonstrate the formation of oriented piezoelectrically active α-quartz thin films directly on silicon. Films are prepared by dip-coating from alcohol/ water solutions of soluble silicic acid precursors plus surfactant or block copolymer structure-directing agents. Solvent evaporation drives the self-assembly of amorphous silica films composed of ordered arrays of pores. An appropriate thermal treatment results on epitaxial quartz films.
We congratulate the authors and specially our group member Martí Gich. You can read the full article
Soft-Chemistry–Based Routes to Epitaxial α-Quartz Thin Films with Tunable Textures
A. Carretero-Genevrier, M. Gich, L. Picas, J. Gazquez, G. L. Drisko, C. Boissiere, D. Grosso, J. Rodriguez-Carvajal, C. Sanchez
www.sciencemag.org SCIENCE VOL 340 17 MAY 2013, 827
You can also read a highlight written by Jeff Brinker in the same issue: Quartz on Silicon. The integration of quartz with silicon may provide a route to fabricate advanced piezoelectric devices. Jeffrey Brinker and Paul G. Clem.
Surface Reactivity of Iron Oxide Nanoparticles by Microwave-Assisted Synthesis; Comparison with the Thermal Decomposition Route
Oana Pascu, Elisa Carenza, Martí Gich, Sònia Estradé, Francesca Peiró, Gervasi Herranz, and Anna Roig
J. Phys. Chem. C, Article ASAP, DOI: 10.1021/jp303204d
The N&N group participates in the @NextGEM_eu project, for which we prepared this video explaining how we work with c.elegans. 🪱
👉 Dr. @PolAlonso1 explains how we use these nematodes and why they are useful for assessing biological effects.
#BioEM #5G
We are thrilled to announce that Dr. @AnnaRoig8 from the @NNgroupICMAB research group (@icmabCSIC, Barcelona, Spain) will be offering a talk on "Opportunities of bacterial nanocellulose in healthcare". This Wednesday at 12.15h at the BBT Weekly Meetings, at @EEBE_UPC
