Tag: encapsulation

Paper in collaboration with ICN2 in RSC Advances

Dual T1/T2 MRI contrast agent based on hybrid SPION@coordination polymer nanoparticles

The study GAby M. Borges, S. Yu, A. Laromaine, A. Roig, S. Súarez-García, J. Lorenzo,D. Ruiz-Molina and F. Novio* has just been published in RSC Advances 2015, 5, 86779–86783.

The paper reports a novel hybrid T1/T2 dual MRI contrast agent by the encapsulation of SPIONs (T2 contrast agent) into an iron-based coordination polymer with T1-weighted signal. This new hybrid material presents improved relaxometry and low cytotoxicity, which make it suitable for its use as contrast agent for MRI.

 

 

ACCEPTED PAPER! Encapsulation of VEGF165 in magnetic PLGA nanocapsules

 

Encapsulation of VEGF165 in magnetic PLGA nanocapsules for potential local delivery and bioactivity into human brain endothelial cells

 

Elisa Carenza, Olivier Jordan, Pablo San Segundo Martínez, Radovan Jiřík, Zenon Starčuk jr., Gerrit Borchard, Anna Rosell* and Anna Roig*  

 

 J. Mater. Chem. B, 2015, 

 Accepted Manuscript 
 DOI: 10.1039/C4TB01895H
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New drug delivery systems based on biodegradable magnetic nanocapsules for targeted delivery of pro-angiogenic proteins, potentially useful in therapeutic angiogenesis