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New paper: The role of reactive oxygen species in liver fibrosis and immune modulation

NN researcher Muling Zeng has published a new article in the journal Redox Biology. The study has been carried out in a collaboration network with de Shenzhen Longgang Second People's Hospital, Premium Research SL, IBIDAPS, University of Barcelona, and the CIBER EHD.

This review examines how ROS function as both signalling molecules and stress inducers, shaping macrophage activity and influencing the development and resolution of fibrosis. Understanding these interactions opens the door to personalised treatments that target ROS and immune cell reprogramming.

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New article: PET imaging of LDL for early detection of atherosclerosis

NN researcher Juan Pellico has published a new article in the journal Chemical & Biomedical Imaging. The study has been carried out in close collaboration with the Centro Nacional de Investigaciones Cardiovasculares Carlos III.

This study introduces a novel PET imaging method to detect low-density lipoprotein (LDL) buildup in atherosclerotic plaques using short-lived gallium-68. The two-step click chemistry strategy enables highly specific, low-radiation imaging, paving the way for earlier and safer cardiovascular disease diagnosis.

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Review article in nanomaterials for cardiac arrhytmia

The NN researcher Anna Laromaine and the former NN PhD student Sumithra Y. Srinivasan published a review article in Advanced Healthcare Materials. The review addresses the development of nanomaterials that can mimic the properties of native cardiac tissue, as well as novel bioevaluation methodologies to evaluate them. Authors advocate for the use of small animals, such as C. elegans, to speed research and bridge the gap between in vitro studies and rodent models.

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New article: Tracking Silica Microparticles in Mice

NN researchers Jan Grzelak, Martí Gich, Anna Roig and Juan Pellico have published a new article in the journal Dalton Trans. The study has been carried out in close collaboration with Rafael T. M. Rosales, from the King's College London.

The study reveals that microparticles with similar size but different shapes do not travel through the body in the same manner. By using PET imaging, this NN-led team discovered that rod-shaped microparticles exit the bloodstream more quickly and concentrate in more in the lungs than spherical particles that primarily accumulate in the liver and spleen. This shape-dependent behaviour could guide the design of new drug delivery systems.

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New article: Bacterial-cellulose, self-adhesive sweat sensors for eco-friendly health monitoring

Pushing bacterial cellulose into a transformative product for wearable sensor applications! Our biosynthesised nanocellulose is used here for the first time as a substrate enabling the screen printing of electrochemical sensors for real-time, non-invasive alcohol monitoring in sweat. The bacterial cellulose sweat alcohol sensor has a highly linear response to alcohol concentration in human sweat, with a minimum detection concentration of 5mM and excellent reproducibility. In addition to sustainability, it shows excellent biocompatibility and self-adhesion. The sensor’s bidirectional functionality also opens new avenues for innovative sweat-sensing system designs.

Eco-Friendly Conformal and Self-Adhesive Electrochemical Sensors for Sweat Monitoring is a new paper by NN researchers Xiaohe Wang, Muling Zeng, Mabel Torrens, Martí Gich, and Anna Roig. It has been published in the journal ACS Applied Materials & Interfaces. This research was done in close collaboration with Pengfei Niu (Tianjin University) and César Fernández Sánchez (IMB-CNM and CIBER-BBN).

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