We congratulate Nerea Murillo and her supervisors Anna Roig and Concepció Domingo for the Extraordinary PhD Award (Premi Extraordinari de Doctorat) for her thesis entitled “MULTIFUNCTIONAL SILICA-BASED NANOPARTICLES FOR BIOMEDICAL APPLICATIONS“. Nerea defended her PhD thesis at ICMAB on 2014, her project aimed to fabricate hybrid (organic-inorganic) complex materials as drug carriers using supercritical fluids. The award ceremony will take place next Friday 18th May at the Auditori de Lletres i de Psicologia of the Autonomous Univeristy of Barcelona.
Nerea Murillo-Cremaes will defend her PhD thesis entitled:
MULTIFUNCTIONAL SILICA-BASED NANOPARTICLES FOR BIOMEDICAL APPLICATIONS
The thesis has been supervised by Dr. Concha Domingo and Dr. Anna Roig.
The thesis jury will be formed by Prof Daniel Ruiz-Molina, Institut Català de Nanociencia i Nanotecnologia, Nanosfun Group, Bellaterra, Catalonia, Prof Vadim Kessler, Swedish University of Agricultural Sciences, Department of Chemistry and Biotechnology, Sweden and Prof Julio San Román, Biomaterials Group, Instituto de Ciencia y Tecnologia de Polimeros (CSIC), Madrid, Spain
This thesis aimed to fabricate hybrid (organic-inorganic) complex materials as drug carriers using supercritical fluids. For that purpose, two main objectives have been addressed: first, evaluation of the potentiality of porous silica-based materials synthesized without using porogenic agents as drug delivery systems; and second, exploiting the utility of SCFs in the synthesis and functionalization of those materials. During the realization of this work, silica-based nanostructured materials have been synthesized, loaded with a model drug, physical and chemically modified on their surface, and their interaction with relevant biological entities and media were investigated.
The International Sol-Gel Conference will be held in Madrid the coming week. The N&N group will be represented by Nerea, Muling and Pengfei. Nerea will give a talk.
The research on drug impregnation of different carriers using supercritical fluids and its in vitro release conducted by Nerea Murillo-Cremaes et al. has been published online in the first 2013 number of The Journal of Supercriticla Fluids as: “Nanostructured silica-based drug delivery vehicles for hydrophobic and moisture sensitive drugs” (Nerea Murillo-Cremaes, Ana M. López-Periago, Javier Saurina, Anna Roig, Concepción Domingo, The Journal of Supercritical Fluids, Volume 73, January 2013, Pages 34–42, doi:10.1016/j.supflu.2012.11.006).