FRIDAY 14th, PhD DEFENSE of NEREA MURILLO

Nerea Murillo-Cremaes will defend her PhD thesis entitled:

MULTIFUNCTIONAL SILICA-BASED NANOPARTICLES FOR BIOMEDICAL APPLICATIONS

The thesis has been supervised by Dr. Concha Domingo and Dr. Anna Roig.

The thesis jury will be formed by Prof Daniel Ruiz-Molina, Institut Català de Nanociencia i Nanotecnologia, Nanosfun Group, Bellaterra, Catalonia, Prof Vadim Kessler, Swedish University of Agricultural Sciences, Department of Chemistry and Biotechnology, Sweden and  Prof Julio San Román, Biomaterials Group, Instituto de Ciencia y Tecnologia de Polimeros (CSIC), Madrid, Spain

 This thesis aimed to fabricate hybrid (organic-inorganic) complex materials as drug carriers  using supercritical fluids. For that purpose, two main objectives have been addressed: first, evaluation of the potentiality of porous silica-based materials synthesized without using porogenic agents as drug delivery systems; and second, exploiting the utility of SCFs in the synthesis and functionalization of those materials. During the realization of this work, silica-based nanostructured materials have been synthesized, loaded with a model drug, physical and chemically modified on their surface, and their interaction with relevant biological entities and media were investigated.